Table 2.

a. Significant prevalent lesions: findings on EUS/FNA and at surgery
Patient ID#	Age/ Sex	Family history	Findings on EUS/FNA	Cytology/CEA	Surgical intervention	Surgical Pathology
1/23	67/F	1 FDR 1SDR	2 cystic lesions in head and body of pancreas; Mild chronic pancreatitis	Suspicious cells. Suspect MCN	Pancreaticoduodenectomy	Multifocal IPMN of borderline malignant potential, predominately involving side branches
2/325	86/F	2 FDR	3 cm cystic lesion body of pancreas	CEA 1765 Focal extracellular mucin	Distal pancreatectomy	IPMN with moderate dysplasia in background of chronic pancreatitis and PanIN2
3/645	58/F	2 FDR	2 cm mass lesion body of pancreas	Neoplastic cells represent MCN vs well-diff adenoca	Distal pancreatectomy	Mod differentiated ductal adenoca, 2.5 cm extending to peripancreatic soft tissue, +vasc and perineural invasion; nonneoplastic pancreas focal chronic pancreatitis; 0/8 + LNs: T3N0
4/776	55/F	1 FDR 1 SDR BRCA+	1 cm cystic lesion prox body; dilated side branch of PD	Cytology negative for malignant cells	Patient declined
5/1063	46/F	1 FDR 1 SDR	1 cm septated cyst possible connection to branch PD	Mucin and glandular cells without atypia	Distal pancreatectomy	PanIN2, focal fibrosis, chronic inflammation
6/1380	83/F	2 FDR	3 cm cystic lesion HOP w few thick septations; 4 cm cystic pancreatic tail lesion; PD dilation	Non diagnostic	Patient declined
7/1476	68/M	1 FDR 3 SDR 1 TDR	PD dilation 6.1 mm head, 3.6 mm in body, 3.0 mm tail	Not done	Pancreaticoduodenectomy	PanIN3, chronic pancreatitis
8/1494	73/M	1 FDR 1 SDR	1 cm single cystic body lesion without septae; 1 cm single cystic head lesion; No PD duct dil	Acellular specimens; non-diagnostic	Distal pancreatectomy	Serous cystadenoma w adjacent retention cysts, PanIN-1B
9/1634	68/F	1 FDR 1 TDR	1 cm hypoechoic, multicystic lesion in head; possible comm. w branch of PD	Cytology negative for malignant cells	Patient declined

Patient ID#	Age/ Sex	Family history	Findings on EUS+/− FNA	Cytology/CEA
1/230	48/M	1 FDR<50	Normal pancreas	n/a
2/241	56/F	2 FDR	Normal pancreas	n/a
3/724	73/F	2 FDR	1 cm simple unilocular round cyst uncinate with no internal structures	Clear thick liquid. Cytology benign. No CEA sent
4/748	53F	2 FDR	5–7 mm cyst body of pancreas no communication with PD	Clear thin liquid. Cytology sparsely cellular, negative for malignancy.
5/1056	59/F	1 FDR 1 SDR	3 cm microcystic mass pancreatic neck, sl dilated PD	FNA unsatisfactory specimen
6/1301	52F	2 FDR	8×4mm cystic lesion; no intramural nodule or mass	Clear yellow fluid Cytology negative for malignant cells No CEA sent