Surgery of the primary
Surgery of the axilla
Radiation: partial breast, post-mastectomy, nodal areas, advanced technologies
Pathology: Ki-67, ER, HER2, grade, other markers
Multi-gene signatures: 21 gene RS, PAM-50, 70 gene signature, EPClin, other
Stroma: extracellular matrix and prognosis
Endocrine therapies: ovarian suppression, tamoxifen, aromatase inhibitors
Chemotherapies: luminal A, duration, regimen
Anti-HER2 therapies: combination, duration
Neo-adjuvant systemic therapy
Bisphosphonates: anti-tumor effects
Follow-up after early breast cancer
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