Table 4.
Results of two-sided Fisher's test of association between the HLA alleles analyzed and the clinical manifestations of dengue (DHF versus DF).
HLA allele | Frequency (%) | Fisher's test | ||
---|---|---|---|---|
DF | DHF | OR (95% CI) | P | |
B44 | 8.48 | 15.83 | 2.02 (0.97–4.24) | 0.047 |
B50* | 1.34 | 5.83 | 4.54 (1.01–27.72) | 0.037 |
DR9* | 3.3 | 0 | 0 (0–1.15) | 0.049 |
DR12* | 3.3 | 0 | 0 (0–1.15) | 0.049 |
DR16* | 2.36 | 7.14 | 3.17 (0.93–12.34) | 0.046 |
HLA: human leukocyte antigen; DF: dengue fever; DHF: dengue hemorrhagic fever; OR: odds ratio; CI: confidence interval; P: P value.
Alleles with overall allelic frequency inferior to 5% are indicated with a star.