Skip to main content
. 2013 Jun 2;2013:140812. doi: 10.1155/2013/140812

Figure 4.

Figure 4

Effects of inhibitors of cell signaling pathways on tryptase (Tt)-induced secretion of IL-6 (a) and TNF-α (b) from astrocytes. Astrocytes were exposed to 1 μg/mL of tryptase in the presence or absence of SB203580 (SB, 20 μM), PD98059 (PD, 20 μM), SP600125 (SP, 20 μM), and LY294002 (LY, 20 μM) at 37°C for 24 h before culture supernatant being collected. Data are presented as the mean ± SEM of four independent experiments. *P < 0.05 versus control groups (Con), # P < 0.05 versus corresponding tryptase treatment groups.