Table 1.
S100b Demographic and Clinical Variables: Distributions by Trajectory Groups
| |
S100b CSF trajectory groups |
S100b serum trajectory groups |
|||||
|---|---|---|---|---|---|---|---|
| Variable | Low group (n=25) | Intermediate group (n=80) | High group (n=33) | p-value | Low group (n=45) | High group (n=35) | p-value |
| Gender, N (%) | |||||||
| Female | 2 (7.1) | 14 (50.0) | 12 (42.9) | 0.022 | 13 (61.9) | 8 (38.1) | 0.614 |
| Male | 23 (20.9) | 66 (60.0) | 21 (19.1) | 32 (54.2) | 27 (45.8) | ||
| Age, years mean±SEM | 36.3±3.0 | 32.3±1.6 | 42.8±2.9 | 0.004 | 35.2±2.2 | 39.5±2.9 | 0.226 |
| BMI mean±SEM | 27.0±0.9 | 26.5±0.6 | 28.1±1.1 | 0.394 | 25.2±0.6 | 28.3±1.2 | 0.054 |
| GCS, median | 7 | 6 | 6 | 0.234 | 6 | 6 | 0.296 |
| ISS mean±SEM | 37.6±2.0 | 33.4±1.1 | 33.9±1.8 | 0.261 | 32.5±1.6 | 37.6±1.6 | 0.032 |
| Hypothermia treatment, N (% yes) | 3 (18.8) | 9 (56.2) | 4 (25.0) | >0.999 | 8 (72.7) | 3 (27.3) | 0.332 |
| Long-bone fracture, N (% fractured) | 2 (18.2) | 6 (54.5) | 3 (27.3) | 0.913 | 4 (66.7) | 2 (33.3) | 0.691 |
| Isolated head injury, N (% with IHI) | 6 (10.0) | 40 (66.7) | 14 (23.3) | 0.081 | 22 (50.0) | 16 (45.7) | 0.821 |
| Mechanism of injury | |||||||
| Automobile/motorcycle | 22 (22.4) | 57 (58.2) | 19 (19.4) | 0.056 | 35 (61.4) | 22 (38.6) | 0.173 |
| Fall/jump | 2 (9.1) | 13 (59.1) | 7 (31.8) | 4 (33.3) | 8 (66.7) | ||
| Other | 0 (0.0) | 10 (58.8) | 7 (41.2) | 5 (50.0) | 5 (50.0) | ||
| Radiological injury type, N (% present) | |||||||
| Subdural hematoma | 14 (17.3) | 47 (58.0) | 20 (24.7) | 0.833 | 25 (51.0) | 24 (49.0) | 0.480 |
| Subarachnoid hemorrhage | 17 (17.4) | 55 (56.1) | 26 (26.5) | 0.421 | 34 (55.7) | 27 (44.3) | 0.781 |
| Diffuse axonal injury | 5 (11.6) | 31 (72.1) | 7 (16.3) | 0.110 | 13 (65.0) | 7 (35.0) | 0.308 |
| Epidural hematoma | 5 (29.4) | 8 (47.1) | 4 (23.5) | 0.295 | 7 (46.7) | 8 (53.3) | 0.570 |
| Contusion | 7 (12.1) | 33 (56.9) | 18 (31.0) | 0.270 | 19 (48.7) | 20 (51.3) | 0.363 |
| Intraventricular hemorrhage | 5 (11.6) | 26 (60.5) | 12 (27.9) | 0.610 | 13 (59.1) | 9 (40.9) | 0.800 |
| Intracerebral hemorrhage | 10 (21.7) | 22 (47.8) | 14 (30.4) | 0.134 | 14 (53.8) | 12 (46.2) | >0.999 |
| Acute care mortality | |||||||
| Dead | 1 (4.2) | 10 (41.7) | 13 (54.1) | <0.001 | 9 (34.6) | 17 (65.4) | 0.015 |
| Alive | 22 (20.9) | 66 (62.9) | 17 (16.2) | 34 (65.4) | 18 (34.6) | ||
SEM, standard error of the mean; BMI, body mass index; GCS, Glasgow Coma Scale; ISS, Injury Severity Scale; IHI, isolated head injury.
Bolded values represent statistically significant comparisons where alpha<0.05.