Table 3A.

Multivariate Logistic Regression Predicting GOS Outcome Using Clinical/Demographic Variables and CSF S100b Trajectory Groups

Independent variable	Odds ratio	95% CI	p-value
Using S100b trajectory groups
Age	0.64	(0.50, 0.83)	0.001
Injury severity (GCS)	1.32	(1.04, 1.70)	0.022
Subdural hematoma	0.34	(0.15, 0.74)	0.007
S100b low group	5.92	(1.64, 21.41)	0.007
S100b intermediate group	3.32	(1.36, 8.07)	0.008
Using mean S100b levels
Age	0.62	(0.47, 0.80)	<0.001
Injury severity (GCS)	1.39	(1.10, 1.77)	0.006
Subdural hematoma	0.42	(0.19, 0.91)	0.027
Contusion	0.48	(0.23, 0.99)	0.049
S100b mean levels	0.95	(0.86, 1.04)	0.229
Using peak S100b levels
Age	0.59	(0.46, 0.77)	<0.001
Injury severity (GCS)	1.36	(1.07, 1.72)	0.013
Subdural hematoma	0.42	(0.20, 0.91)	0.027
S100b peak levels	0.83	(0.64, 1.09)	0.176

GOS, Glasgow Outcome Scale; CSF, cerebrospinal fluid; CI, confidence interval; GCS, Glasgow Coma Scale.

Bolded values represent statistically significant comparisons where alpha<0.05.