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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Arthritis Rheum. 2013 Feb;65(2):513–518. doi: 10.1002/art.37776

Figure 3.

Figure 3

Whole blood transcriptional profile of the patient with untreated Blau syndrome overlaps with that of systemic-onset juvenile idiopathic arthritis (SoJIA) patients. A, Expression values of transcripts from the patient with Blau syndrome at baseline (as in Figure 1A) were compared with those from patients with systemic-onset JIA (normalized to values in 18 matched healthy controls). In this analysis, 1,560 transcripts were included as they were common to the 2 Illumina bead array chips used in original analyses of Blau syndrome and systemic-onset JIA. As shown in the boxed area, only 46 transcripts were up-regulated in Blau syndrome but not in systemic-onset JIA. B, The 46 genes were analyzed by IPA. A leptin receptor–centered network was revealed. See Figure 2 for other definitions.