Table 7.
Mapping | Sens | Spec | PPV | NPV | ||
---|---|---|---|---|---|---|
Solution I | Barton: | .84 | .55 | .79 | .63 | |
Huerta1: | .86 | .41 | .75 | .59 | ||
A: Threshold: 12 | A: 3/3 criteria | |||||
B: Threshold: 1 | B: 2/4 criteria | |||||
| ||||||
Solution II | Barton: | .77 | .94 | .96 | .66 | |
Huerta: | .72 | .94 | .96 | .62 | ||
A: Threshold: ROC3 | A: 3/3 criteria | |||||
B: Threshold: 1 | B: 2/4 criteria | |||||
| ||||||
Solution III | Barton: | .85 | .82 | .91 | .72 | |
Huerta: | .85 | .83 | .91 | .72 | ||
A: Threshold: ROC | A: 2/3 criteria | |||||
B: Threshold: 1 | B: 2/4 criteria | |||||
| ||||||
Solution IV | Barton: | .81 | .91 | .95 | .70 | |
Huerta: | .76 | .91 | .95 | .65 | ||
A: Threshold: ROC | A: 3/3 criteria | |||||
B: Threshold: ROC | B: 1/4 criteria | |||||
| ||||||
Solution V | Barton: | .89 | .77 | .89 | .77 | |
Huerta: | .89 | .79 | .90 | .77 | ||
A: Threshold: ROC | A: 2/3 criteria | |||||
B: Threshold: ROC | B: 1/4 criteria | |||||
| ||||||
Solution VI | Barton: | .93 | .74 | .88 | .84 | |
Huerta: | .93 | .78 | .89 | .84 | ||
A: Threshold: ROC | A: 2/3 criteria | |||||
B: Threshold: 1 | B: 1/4 criteria |
Huerta et al. (2012) mappings were contrasted with those determined by the current authors, in order to evaluate two sets of expert mappings of ADI-R and ADOS symptoms.
Threshold of 1 point on any ADI-R or ADOS item that maps on to this symptom is sufficient for endorsement; Per communication with Cathy Lord.
ROC-defined cutoffs were determined by examining the distribution of the sum of ADI-R and ADOS items that contributed to each DSM-5 criterion, and identifying the cut score that balanced sensitivity and specificity (Domain A: highest score that maintained a sensitivity of .90; Domain B: lowest score that maintained specificity of .50 or higher; see Tables 4-5).