Table 4. Previous reports of lysine acetylations for the acetylated proteins associated with heart failure.

The lysine acetylated proteins common to both models of heart failure are listed with any known acetylation sites previously reported in the literature and the model in which the acetylations were documented.

Protein	Reported Acetylation Site in Literature	Reference	Model
Dihydrolipoamide dehydrogenase	Lysine 127	[8]	mouse liver
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa	Lysine 81, 104, 375	[8]	mouse liver
ATP synthase beta subunit	Lysine 133, 259, 522	[8]	mouse liver
Ubiquinol-cytochrome c reductase core protein I	Lysine acetylation detected but no specific site was determined	[25]	mouse liver
Actin, alpha 1, skeletal muscle	Lysine acetylation detected but no specific site was determined	[7]	human
Long-chain acyl-CoA dehydrogenase	Lysine 42 (functionally significant), 156, 189, 240, 254, 318, 322, 358	[14]	SIRT3 KO mouse liver
Muscle creatine kinase	Lysine acetylation detected but no specific site was determined	[16]	mouse skeletal tissue
Aspartate aminotransferase, cytoplasmic	Lysine 154	[7]	human
Malate dehydrogenase	Lysine 165, 185, 301, 307, 314, 329, 335	[7],[8],[11]	mouse liver, human
Pyruvate dehydrogenase (lipoamide) beta	Lysine 354	[7]	human