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. Author manuscript; available in PMC: 2013 Jun 17.
Published in final edited form as: Chem Soc Rev. 2012 Mar 5;41(7):2971–3010. doi: 10.1039/c2cs15344k

Fig. 3.

Fig. 3

Components of CALAA-01 (Calando Pharmaceuticals-01) – a targeted NP for siRNA delivery: (a) CDP: water-soluble, linear cyclodextrin-containing polymer, AD: adamantane (AD)-PEG conjugate (PEG MW of 5000) (AD-PEG), and Tf-PEG-AD: an adamantane conjugate of PEG (PEGMWof 5000) conjugated with human transferrin (Tf) ligand. (b) CALAA-01 is formulated via a single self-assembly process of four individual components. Figure taken from Davis, M et al.18