Fig. 9.
Polymer-lipid hybrid ‘Nanoburr’ particles. A: Polymer-drug conjugate synthesis (Ptxl-PLA), B: HPLC characterization of Ptxl and Ptxl-PLA polymer, C: Nanoburr synthesis via polymer lipid, and lipid-PEG self-assembly, D: TEM image of Nanoburrs (stained with 3% uranyl acetate), E: Dynamic light scattering measurements (DLS) pre and post peptide conjugation, F: Zeta potential measurements pre and post peptide onjugation, and G: in vitro drug release profile of Ptxl from Nanoburr NPs. Figure taken from Chan et al.147