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. Author manuscript; available in PMC: 2013 Jun 17.
Published in final edited form as: J Dermatol Sci. 2012 Feb 24;66(1):3–11. doi: 10.1016/j.jdermsci.2012.02.007

Figure 3. Wnt3a and Dkk1 modulate the propagatory patterns of the regenerative hair wave.

Figure 3

Administration of Wnt3a protein coated beads causes premature anagen initiation surrounding telogen hair follicles (A, C), while administration of Dkk1, a Wnt antagonist, prevents normal progression of the physiological anagen spreading wave (E). Control BSA beads can’t induce anagen re-entry (B, D). Red dotted outlines on A, C mark boundaries between anagen and telogen skin. Adopted from Plikus et al., 2011.