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. Author manuscript; available in PMC: 2013 Jun 17.
Published in final edited form as: Arthritis Rheum. 2010 Mar;62(3):781–790. doi: 10.1002/art.27288

Figure 2. Potential OA candidate genes on chromosome 6, 8, and 14.

Figure 2

Genes listed in bold over the peaks represent potential novel candidate genes associated with biomarkers of OA in this study that have potential biological relevance for OA based on the literature. Genes listed without bold type over the peaks represent candidate genes linked previously to OA. The # sign indicates that the genes are less than 10 cM from the border of the 1-LOD drop support interval. ANGPT2=angiopoietin 2; DEFB4=beta-defensin 4; ANK1=ankyrin 1; PLAT=plasminogen activator, tissue; PLAG1= pleomorphic adenoma gene 1; COL22A1=collagen, type XXII, alpha 1; WISP1=wnt-1-induced secreted protein 1; HFE=hemochromatosis; COL11A2=collagen, type XI, alpha 2; TNF=tumor necrosis factor; COL10A1=collagen, type X, alpha 1; ESR2=Estrogen receptor 2; DIO2=Type II iodothyronine deiodinase; FLRT2=Fibronectin leucine-rich transmembrane protein 2.