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Biochemical and viral serological markers during the course of the disease, before and after the introduction of tenofovir. ALT, Alanine aminotransferase (U/L); INR, International normalized ratio; HBsAg, hepatitis B surface antigen; HBeAg, Hepatitis B e antigen; Anti-HBc IgM, anti-hepatitis B core IgM antibody; HBV DNA, Hepatitis B DNA; Anti-HBs, anti-hepatitis B surface antibody.
