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Effects of leukotrienes B4 and D4 on SCH28080-sensitive H,K-ATPase specific activity. Gastric microsomes suspended in ATPase assay buffer at pH 7.4 were incubated for 30 min with varying concentrations of leukotriene B4 or leukotriene D4 and ATPase activity was then measured at pH 7.4. The data-points show mean ± s.e. from three independent assays in each of which SCH28080-sensitive ATPase activity was measured in triplicate.
