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Recursive partitioning using ‘Top SNPs’ with Total Therapy 2 (TT2) model. Recursive partitioning branching tree displaying the four single nucleotide polymorphisms (SNPs) used in the model: rs3766934 (EPHX1); rs3783408 (Gsk3β); rs1052637 (DDX18); and rs3181366 (TNSF8). The SNP genotypes are identified: EPHX1(GT/TT versus GG); Gsk3 β (GG versus AG/AA); DDX18 (CC versus CG/CC); and TNFSF8 (CC versus CT/TT). The appended table shows the univariate P-values for each SNP and SNP function.
