Table 3.
Clinical Characteristics of the Cohort (N = 265) at Mean Age 22 According to Quartile of Metabolic Syndrome Cluster Score at Mean Age 13
| Variable | Quartile 1 (N = 59) (range −1.440 to −0.411) | Quartile 2 (N = 67) (range −0.400 to −0.073) | Quartile 3 (N = 73) (range −0.072 to 0.317) | Quartile 4 (N = 66) (range 0.318 to 2.044) | P-Trend |
|---|---|---|---|---|---|
| Body Mass Index (kg/m2) | 23.2 ± 4.9 | 25.4 ± 5.5 | 26.9 ± 6.5 | 29.0 ± 7.6 | <0.0001 |
| Waist Circumference (cm) | 78.9 ± 11.6 | 84.6 ± 14.9 | 88.6 ± 14.5 | 95.3 ± 18.7 | <0.0001 |
| Body Fat (%) | 24.7 ± 12.2 | 25.9 ± 11.9 | 29.7 ± 12.8 | 33.1 ± 11.8 | <0.0001 |
| Total Cholesterol (mg/dL) | 149.6 ± 27.7 | 160.7 ± 36.9 | 162.6 ± 28.0 | 169.8 ± 29.6 | 0.0004 |
| LDL Cholesterol (mg/dL) | 82.8 ± 23.4 | 95.6 ± 31.7 | 97.5 ± 23.7 | 105.7 ± 26.7 | <0.0001 |
| HDL Cholesterol (mg/dL) | 53.1 ± 13.2 | 46.5 ± 10.3 | 44.2 ± 10.0 | 41.5 ± 9.1 | <0.0001 |
| Triglycerides (mg/dL) | 71.7 ± 35.9 | 93.1 ± 51.9 | 104.8 ± 59.1 | 113.3 ± 56.7 | <0.0001 |
| Systolic Blood Pressure (mmHg) | 106.5 ± 9.2 | 109.7 ± 10.6 | 111.3 ± 8.8 | 112.8 ± 10.4 | 0.0004 |
| Diastolic Blood Pressure (mmHg) | 64.5 ± 9.2 | 66.3 ± 9.7 | 63.6 ± 9.6 | 66.2 ± 12.1 | 0.65 |
| Fasting Glucose (mg/dL) | 83.1 ± 10.9 | 85.5 ± 8.7 | 85.0 ± 9.2 | 88.5 ± 8.4 | 0.002 |
| Fasting Insulin (mU/L) | 7.6 ± 10.0 | 8.0 ± 5.0 | 8.4 ± 5.1 | 11.2 ± 21.6 | 0.28 |
| Mlbm (mg/kg LBM/min) | 13.0 ± 4.4 | 11.4 ± 3.5 | 11.6 ± 4.2 | 11.0 ± 3.8 | 0.02 |
| MetS Cluster Score | −0.38 ± 0.60 | 0.06 ± 0.64 | 0.24 ± 0.66 | 0.57 ± 0.64 | <0.0001 |
Data are presented as mean ± standard deviation. All analyses were adjusted for sex, race, and age.