Table 3.
Variable | Median Value For Patients with OI |
Median Value For Patients without OI |
Logistic Regression (P-value) |
---|---|---|---|
Abs # CD4+ T Cells (cell # /μl) | 44 | 137 | 0.02 without age in model |
% CD8+ T Cells | 44 | 14 | <0.0001 |
% CD57+/CD28−/CD8+ T cells | 9 | 3 | <0.02 |
% CD25+/CD3+T Cells | 22 | 40 | <0.016 |
% TCRγδ T cell subset | 2.3 | 0.97 | <0.017 |
% ‘activated’ HLA-DR+ T cells | 53 | 38 | <0.009 |
% ‘NKT’ CD3+/CD56+ T cells | 8 | 4 | <0.01 |
% IFNγ Secreting T cells | 18 | 4 | <0.006 |
Confounders tested: Race, age, gender, weight, CMV status, HLA mismatch, malignancy, TBI, GvHD, High Dose steroid pulse (yes, no), Anti-CD25/Daclizumab pulse (yes, no), infused total cell dose/kg, CD34+ cell/kg, CD3+ T cell dose/kg.
OI, opportunistic infection.