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. Author manuscript; available in PMC: 2013 Jun 17.
Published in final edited form as: Semin Hematol. 2010 Jan;47(1):22–36. doi: 10.1053/j.seminhematol.2009.10.009

Table 5. Cytolytic activity of ex-vivo expanded natural killer (NK) cells in AB/CY; day 7 vs. day 2.

NK cytotoxicity was measured by standard europium release assay using as tumor targets: an NK sensitive cell line, K562, a LAK sensitive cell line Daudi, and human cell lines AML, Kasumi-1and neuroblastoma, SYSY5Y at an effector /target ratio of 20:1.

Tumor target % Cytotoxicity @ d2
(Mean±SEM))		 % Cytotoxicity @ d7
(Mean±SEM))		 p value
K562 53.83±3.91 71.46±0.81 p<0.001
Daudi 31.83±1.8 63.95±0.74 p<0.001
SYSY5 57.53±3.41 76.77±6.59 p<0.05
Kasumi 38.0±1.16 56.65±0.47 p<0.001

Reprinted from Exp Hematol, Ayello J, van de Ven C, Cairo E, et al., Characterization of natural killer (NK) and natural killer-like T (NKT) cells derived from ex-vivo expanded and activated cord blood mononuclear cells: Implications for adoptive cellular immunotherapy (ACI), ©2009, with permission from Elsevier.