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. Author manuscript; available in PMC: 2013 Sep 18.

Published in final edited form as: J Am Coll Cardiol. 2012 Aug 29;60(12):1079–1085. doi: 10.1016/j.jacc.2012.06.015

Table 4.

c-Statistics, IDI, and NRI for the assessment of CAC and RAC in addition to FRS in predicting all-cause and cardiovascular mortality

	All-cause Mortality	Cardiovascular Mortality
	c-Statistics	IDI	NRI	c-Statistics	IDI	NRI
1. Base model alone (hard FRS)	0.69 (0.65–0.73)	/	/	0.77 (0.705–0.831)	/	/
2. Base plus CAC	0.73 (0.694–0.77)	0.016 vs #1	20.8% vs #1	0.83 (0.774–0.880)	0.011	12.5% vs #1
p values (vs. model 1)	0.001	< 0.0001	< 0.0001	0.049	0.001	0.05
3. Base plus CAC plus RAC	0.77 (0.74–0.81)	0.036 vs #1 0.020 vs #2	30.3% vs. #1 14.4% vs #2	0.84 (0.79–0.89)	0.018 vs #1 0.008 vs #2	14.2% vs #1 1.7% vs #2
p values (vs model 1)	< 0.0001	< 0.0001	< 0.0001	0.03	0.001	0.06
p values (vs. model 2)	0.0002	< 0.0001	0.002	0.134	0.002	0.75

IDI = integrated discrimination improvement; NRI = net reclassification index.