Table 2.
Risk factors for overall survival in stage IB NSCLC
| |
Univariate analysis |
Multivariate analysis (Cox hazard model) |
||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| Age |
1.053 (1.015-1.094) |
0.006 |
1.031 (0.995-1.069) |
0.092 |
| Sex (female vs. male) |
0.571 (0.254-1.284) |
0.175 |
0.689 (0.300-1.584) |
0.381 |
| ECOG 1 (vs. 0) |
2.343 (1.128-4.864) |
0.022 |
1.717 (0.804-3.668) |
0.163 |
| 2 (vs. 0) |
0 |
0.976 |
0 |
0.977 |
| Pneumonectomy |
1.389 (0.421-4.585) |
0.590 |
… |
… |
| Tumor size |
0.980 (0.947-1.015) |
0.264 |
… |
… |
| Numbers of dissected lymph nodes |
0.987 (0.956-1.018) |
0.408 |
… |
… |
| Adenocarcinoma (vs. non-adenocarcinoma) |
0.898 (0.437-1.845) |
0.769 |
… |
… |
| Differentiation (moderate to poor vs. well) |
1.317 (0.638-2.944) |
0.419 |
… |
… |
| Lymphovascular invasion |
0.494 (0.115-2.110) |
0.341 |
… |
… |
| Pleural invasion (pl2 and pl1 vs. pl0) |
1.228 (0.524-2.875) |
0.637 |
… |
… |
| Platinum based chemotherapy (vs. no adjuvant therapy) | 0.360 (0.159-0.813) | 0.014 | 0.428 (0.184-0.998) | 0.049 |