Table 3.
Risk factors for disease-free survival in stage IB NSCLC
| |
Univariate analysis |
Multivariate analysis (Cox hazard model) |
||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| Age |
1.032 (1.004-1.062) |
0.028 |
1.022 (0.994-1.051) |
0.132 |
| Sex (female vs. male) |
0.795 (0.427-1.480) |
0.470 |
… |
… |
| ECOG 1 (vs. 0) |
1.679 (0.895-3.149) |
0.107 |
1.552 (0.802-3.002) |
0.192 |
| 2 (vs. 0) |
0.802 (0.107-5.989) |
0.829 |
0.980 (0.113-8.464) |
0.985 |
| Pneumonectomy |
1.176 (0.421-3.290) |
0.757 |
… |
… |
| Tumor size |
0.998 (0.970-1.027) |
0.897 |
… |
… |
| Numbers of dissected lymph nodes |
0.984 (0.960-1.010) |
0.207 |
… |
… |
| Adenocarcinoma (vs. non-adenocarcinoma) |
1.220 (0.675-2.206) |
0.509 |
… |
… |
| Differentiation (moderate to poor vs. well) |
1.675 (0.874-3.211) |
0.120 |
… |
… |
| Lymphovascular invasion |
0.827 (0.322-2.124) |
0.692 |
… |
… |
| Pleural invasion (pl2 and pl1 vs. pl0) |
0.953 (0.458-1.983) |
0.897 |
… |
… |
| Platinum based chemotherapy (vs. no adjuvant therapy) | 0.454 (0.244-0.847) | 0.013 | 0.507 (0.263-0.978) | 0.043 |