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. 2013 Jun 13;13:283. doi: 10.1186/1471-2407-13-283

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Copyright © 2013 Coumans et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Probability of distant metastasis by T-stage for patients who are N_XM₀. Total n = 38715, number of DM n = 3550. Whiskers indicate 95% confidence intervals determined using Poisson statistics. Below the T-stage further statistics are shown, including median diameter in mm, number of patients included, number of patients with a DM as well as mean and standard deviation of time to DM. The model was fit to 25% of the data for T_1B tumors. In this subset of the data, there were 42 occurrences of DM in 1489 patients (2.8%) compared to 195 occurrences in 5957 patients (3.3%). Probability of DM for T_1A, T_1C and T₂ was predicted using the model fit to T_1B data.