Table 1.
Human breast cancer values for doubling time
| |
|
Tumor |
Doubling time (months) |
|
|---|---|---|---|---|
| Publication | N | size (mm) | Median | Range |
| Lundgren 1977 [27] |
13 |
N/A |
6.9 |
1.4 – 13.0 a |
| Heuser 1979 [28] |
32 |
14 |
10.6 b |
3.6 – 31.0 a |
| Von Fournier 1980 [29] |
100 |
17 |
6.6 b |
2.1 – 20.6 c |
| Galante 1981 [30] |
196 |
N/A |
2.0 |
N/A |
| Tabbane 1989 [31] |
75 |
N/A |
3.8 |
0.5 – 25.3 a |
| Kuroishi 1990 [32] |
142 |
N/A |
5.7 b |
0.4 – 42.4 a |
| Spratt 1993 [19] |
448 |
9 |
8.5 |
5.0 – 15.7 d |
| Peer 1993 [33] |
236 |
>10 |
5.0 |
1.5 – 17.1 e |
| Tilanus-Linthorst 2005 [34] |
47 |
12 |
2.0 b |
0.4 – 18.6 a |
| Weedon-Felkjaer 2008 [35] |
969 |
15 |
3.1 |
1.0 – 9.6 d |
| Millet 2011 [36] | 37 | 9 | 11.2 b | −222.9 – 146.6 a |
N/A: not available, a minimum-maximum, b mean, c 2.5-97.5 percentile, d 25-75 percentile, e 68% confidence interval.