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. 2013 Jun 17;13(Suppl 2):S3. doi: 10.1186/1471-2458-13-S2-S3

Table 1.

Data sources of key DALYs averted model parameters

Parameter Data Source
Burden (macro models) Mortality Data:
■ WHO Global Burden of Disease reports [[18,26]
■ Demographic and Health Surveys (DHS)[27]
■ Multiple Indicator Cluster Surveys [28]
Morbidity Data:
■ DHS
■ Published literature

Risk of Infection (micro models) ■ Published literature
■ UNAIDS or WHO reports (for epidemic data) [29,30]
■ PSI population-based surveys (for behaviors such as sexual behavior or drug use behavior) [31]

Efficacy/Effectiveness ■ Published randomized controlled trials, community randomized trials
■ Child Health Epidemiology Reference Group (CHERG) reviews [32]
■ Cochrane Literature Review [33]
■ WHO Global Burden of Disease reports

Attrition, or Wastage ■ PSI supply chain studies (as of 2011)
■ PSI population-based surveys (as of 2011)
■ Communication with PSI programmers
Note: Wastage data are rarely available in the published literature so wastage levels were assumed until 2011.

Utilization (including adherence) Utilization Data:
■ PSI population-based surveys
■ USAID CYP conversion factor for family planning products [34]
■ Published literature
Adherence Data:
■ Published literature
■ PSI product usage studies (e.g., pill counts in HAART program)
■ Communication with experts in the field
Note that protective efficacy/effectiveness studies, such as CHERG reviews, are likely to have adherence/compliance data embedded in them already.

Time frame Defined as one year. For products/services with lifespans longer than one year, all years of impact are counted in the year of distribution.

Disability Weight Global Burden of Disease and Risk Factors [18]

Duration of Disease or Disability Published literature

Age at Death due to Disease or Disability ■ Age distribution data of age at death
■ Weighted estimates of age at death based on age group data from Global Burden of Disease and Risk Factors [18]

Life Expectancy WHO, 2011 (for Japanese life expectancy data) [35]