Table 2.

Absolute methylation levels of the different tissues per gene and per CpG site

	CD34+ MNC	CD34– MNC	Pooled MNC	Placental tissue	Wharton jelly
IGF2 DMR (total)	0.55 (0.14)	0.50 (0.13)	0.50 (0.13)	0.54 (0.16)	0.65 (0.13)†*
IGF2 DMR CpG 3	0.59 (0.05)	0.52 (0.02)	0.52 (0.02)	0.59 (0.07)	0.66 (0.07)†
IGF2 DMR CpG 4	0.64 (0.18)	0.59 (0.18)	0.59 (0.18)	0.58 (0.25)	0.77 (0.11)
IGF2 DMR CpG 6.7	0.43 (0.06)	0.39 (0.03)	0.39 (0.03)	0.44 (0.03)	0.52 (0.06)†
H19 DMR (total)	0.30 (0.02)	0.31 (0.02)	0.31 (0.02)	0.25 (0.02)†	0.28 (0.03)†*
H19 DMR CpG 2	0.28 (0.01)	0.29 (0.01)	0.29 (0.01)	0.26 (0.01)	0.27 (0.04)
H19 DMR CpG 9.10	0.31 (0.01)	0.31 (0.02)	0.31 (0.02)	0.26 (0.03)	0.30 (0.04)
H19 DMR CpG 12	0.28 (0.02)	0.29 (0.01)	0.29 (0.01)	0.23 (0.02)†	0.26 (0.02)†
H19 DMR CpG 13	0.30 (0.01)	0.31 (0.01)	0.31 (0.01)	0.24 (0.01)†	0.28 (0.03)
H19 DMR CpG 17	0.34 (0.02)	0.35 (0.01)	0.35 (0.01)	0.25 (0.03)†	0.31 (0.03)*

Data presented as mean (standard deviation). Analysis of variance testing between the different tissue groups. Bonferroni correction was applied to all P values to adjust for multiple comparisons. DMR differentially methylated region; MNC mononuclear cells.

†P <0.05 versus pooled MNC (pairwise comparisons).

*P <0.05 versus placenta (pairwise comparisons).