Table 2. Virus-associated cytokine/chemokine (pg/ml) responses with and without PBMCs in Calu-3 infected cells (n = 4).

Cytokine/Chemokine	Medain (Range in pg/ml)			P value
	PBMC	HRV 14	HRV 16	HRV14 vs HRV16	HRV14 (N) vs HRV14(Y)	HRV16 (N) vs HRV16(Y)
IP-10	N	1559 (1006-1765)	355 (245-462)	<0.001*	0.012*	0.163
	Y	885 (752-900)	434 (382-553)	0.003*
MIP-1β	N	7.0 (5.6-8.3)	27.5 (11.9-92.9)	0.003*	<0.001*	0.502
	Y	353 (209-439)	40.8 (16.4-77.6)	0.003*
IFN-α	N	61.2 (29.2-101)	66.8 (30.1-131)	0.502	<0.001*	0.003*
	Y	1447 (1304-2375)	146 (141-212)	0.017
IL-28A	N	21.1 (12.3-22.8	33.0 (16.5-55.5)	0.232	0.001*	0.578
	Y	236 (197-251)	52 (11.4-58)	0.014
ENA-78	N	73733 (68961-85868)	17609 (14076-21402)	0.017	<0.001*	0.352
	Y	13862 (11461-16022)	16752 (11048-19686)	0.208
MCP-2	N	8.4 (5.9-11.8)	5.9 (5.2-15.2)	0.502	<0.001*	<0.001*
	Y	4308 (3883-4902)	1511 (1012-2338)	0.016*

“N” indicates No PBMC exposure and “Y” indicates PBMC exposure. Two-factor ANOVA models were used. Four pairwise comparisons were made between HRV 14 and HRV 16 with and without PBMCs. * indicates statistical significance at 0.0125 level.