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. 2013 Jun 17;8(6):e66566. doi: 10.1371/journal.pone.0066566

Table 1. Composition of the dataset.

CYP isoform Tested compounds Activecompounds Active only against this CYP Active also against:
1A2 2C9 2C19 2D6 3A4
1A2 12 634 5 838 (46%) 1 395 2 011 3 252 1 272 2 565
2C9 12 264 4 024 (33%) 370 2 011 3 022 800 2 115
2C19 12 834 5 763 (45%) 562 3 252 3 022 1 363 3 012
2D6 13 276 2 545 (19%) 622 1 272 800 1 363 1 252
3A4 12 383 5 165 (42%) 889 2 565 2 115 3 012 1 252