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. 2013 Jun 17;8(6):e66106. doi: 10.1371/journal.pone.0066106

Figure 2. Fibrosis-related genes after eight weeks of MCD diet.

Figure 2

MCD-fed CCL3−/− mice show a significantly altered expression of the fibrosis-related genes Col1a1, TIMP1 and MMP9 compared to wild-type mice. However, mRNA expression of TGF-β1 does not vary in CCL3−/− mice (A). α-SMA expression is significantly decreased in CCL3−/− mice after MCD diet. Representative α-SMA staining is shown in the left panel (x100 magnification, B). Data are expressed as means ± SEM of eight mice per group. *P<0.05.