Figure 1. Amino acid residues preferentially recognized by VY8-specific CD8+ T cells.
Graphical representation showing relative preference for amino acid residues recognized by VY8-specific T cell lines and clones based on the CPL scan data shown in Figure S1. Responses >20% were included. A web-based application, WebLogo 3 (http://weblogo.threeplusone.com/), was used to generate the graphic. Colours represent physicochemical properties: polar (G, S, T, Y and C), green; neutral (Q and N), purple; basic (K, R and H), blue; acidic (D and E), red; hydrophobic (A, V, L, I, P, W, F and M), black. The index residues at each position are outlined in yellow. Residue size is proportional to T cell recognition preference.