Table 7. The Gene Ontology results of the subnetwork for AML of leukemia dataset.
Subnetwork | Elements | GO Number | Ontology Description | P-value |
AML-1 | IGKC IGLC3 IGHG3 | GO:0006958 | complement activation, classical pathway | 1.6×10–6 |
AML-2 | FOSB JUNB | GO:0071277 | cellular response to calcium ion | 4.3×10–5 |
AML-3 | IFI30 FCER1G | GO:0019886 | antigen processing and presentation of | 2.0×10–4 |
exogenous peptide antigen via MHC class II | ||||
GO:0042590 | antigen processing and presentation of | 3.8×10–4 | ||
exogenous peptide antigen via MHC class I | ||||
AML-3 | FCER1G CTSB | GO:0009897 | external side of plasma membrane | 4.0×10–4 |
AML-3 | IFI30 CTSB | GO:0043202 | lysosomal lumen | 6.2×10–5 |
AML-4 | The entire subnetwork | GO:0008009 | chemokine activity | 1.4×10–5 |
AML-5 | SLC4A1 HBB | GO:0015701 | bicarbonate transport | 6.1×10–6 |
AML-6 | CCL3 CCL4 | GO:0031730 | CCR5 chemokine receptor binding | 1.6×10–7 |
GO:0031726 | CCR1 chemokine receptor binding | 1.6×10–7 | ||
AML-7 | The entire network | GO:0070488 | neutrophil leukocyte aggregation | 1.7×10–7 |
GO:0002523 | leukocyte migration involved in inflammatory response | 3.7×10–6 |
The first column (Subnetwork) reports the name of the subnetwork introduced in Figure 4. The second column (Elements) presents the elements of subnetwork of which the functional and biological relationship are analyzed based on the GO annotation.