Table 2.

List of downregulated genes

Symbol	Gene name	Ascl1	FC	Ptf1a	FC
Pdyn	Prodynorphin	++	2.7	n.s.
Gad1	Glutamic acid decarboxylase 1	++	2.1	++	3.1
Cacna2d3	Calcium channel, voltage-dependent, α2/δ3	++	2.1	++	2.5
Pax8	Paired box gene 8	++	2.2	++	3.9
Kcnip2	Kv channel-interacting protein 2	++	3.7	n.s.
Pnoc	Prepronociceptin	++	3.8	++	3.7
Prkcq	Protein kinase Cθ	++	2.4	++	3.9
Neurod1	Neurogenic differentiation 1	++	2.9	n.s.
Slc35d3	Solute carrier family 35, member D3	++	4.3	n.s.
Neurod2	Neurogenic differentiation 2	++	3.1	n.s.
Pou4f2	POU domain, class 4, transcription factor 2	++	2.9	n.s.

The transcriptome of dorsal horn cells of Ascl1^−/− mice was compared with littermate controls using Affymetrix expression arrays. The gene symbol and name of the respective genes are depicted. In columns 3 and 5, it is indicated whether the downregulation of the respective gene was called highly significant (++, corrected p ≤ 0.005), significant (+, corrected p ≤ 0.05), or not significant (n.s.). In columns 4 (Ptf1a vs control) and 6 (Ascl1 vs control), the fold change (FC) the respective gene was downregulated according to the Affymetrix results is indicated.