Fig. 6.

Top Panel (A)–(C) representative CD14/CD16 dot plots of monocytes from (A) a rural African donor, (B) an urban African donor and (C) a Caucasian donor. Cells are gated according to the strategy described in Fig. 1. Bottom panel (D) Bar graphs illustrating the differences in mean and SEM of monocyte subset proportions between rural Africans (n = 21, filled bars), Africans from urban environments (n = 5, grey bars) and Caucasians (n = 21, open bars). 1: regCD14; 2: dpCD14; 3: HLADRhi; 4: dpCD16; 5: regCD16. P values are from the Mann–Whitney test with an applied Bonferonni correction. Significant p values (p < 0.0167) are indicated with *.