Fig. 7.
Stability of AR-67 in cell culture media. The time course of AR-67 interconversion was studied in cell culture media (pH 7.4, 37°C, 5% CO2) after the addition of 1 μM of AR-67 carboxylate (A) or 1 μM of AR-67 lactone (B). Data are represented as the percentage ratio concentration of carboxylate or lactone over total drug.
