Table 5.
Case-fatality rate and RR of death for neonatal sepsis, Korea, 1997–1999
| Early-onset clinical sepsis |
No. deaths | Case-fatality rate (%) |
RR (95%CI) | Adjusted RR (95%CI) † |
|
|---|---|---|---|---|---|
| Hospitalization year | |||||
| 1997 | 319 | 28 | 8.8 | 1.0 | |
| 1998 | 287 | 12 | 4.2 | 0.5 (0.23–0.91) | |
| 1999 | 216 | 11 | 5.1 | 0.6 (0.27–1.15) | |
| Birth hospital | |||||
| Study hospital (inborn) | 595 | 43 | 7.2 | 1.0 | |
| Non-study hospital (outborn) | 227 | 8 | 3.2 | 0.5 (0.22–1.01) | |
| Sex | |||||
| Girls | 366 | 18 | 4.9 | 1.0 | 1.0 |
| Boys | 456 | 33 | 7.2 | 1.5 (0.84–2.73) | 2.5 (1.21–5.06) |
| Delivery method | |||||
| Vaginal delivery | 389 | 22 | 5.7 | 1.0 | |
| Cesarean section | 390 | 25 | 6.4 | 1.1 (0.63–2.06) | |
| Others | 43 | 4 | 9.3 | 1.7 (0.56–5.22) | |
| Prolonged ROM (h) | |||||
| ≥18 | 116 | 5 | 4.3 | 1.0 | |
| <18 | 657 | 41 | 6.2 | 1.5 (0.57–3.82) | |
| Unknown | 49 | 5 | 10.2 | 2.5 (0.70–9.15) | |
| Birthweight (g) | |||||
| >2500 | 535 | 13 | 2.4 | 1.0 | 1.0 |
| 1501–2500 | 216 | 8 | 3.7 | 1.5 (0.63–3.78) | 1.0 (0.37–2.60) |
| ≤1500 | 71 | 30 | 42.3 | 29.4 (14.24–60.62) | 11.3 (4.55–28.21) |
| Gestational age (weeks) | |||||
| ≥37 | 537 | 14 | 2.6 | 1.0 | |
| 33–36 | 172 | 3 | 1.7 | 0.7 (0.19–2.34) | |
| ≤32 | 109 | 34 | 31.2 | 16.9 (8.69–33.02) | |
| Unknown | 4 | 0 | – | – | |
| Apgar score, 5 min | |||||
| ≥8 | 446 | 7 | 1.6 | 1.0 | 1.0 |
| ≤7 | 179 | 39 | 21.8 | 17.5 (7.64–39.93) | 6.8 (2.62–17.55) |
| Unknown | 197 | 5 | 2.5 | 1.63 (0.51–5.21) | 1.64 (0.50–5.35) |
| Total | 822 | 51 | 6.2 |
†
Adjusted relative risks were obtained on multiple logistic analysis; sex, birthweight and Apgar score were included in the model. All variables are adjusted for all others.
Patients with unknown prognosis (n = 14) were excluded from this analysis.
CI, confidence interval; early onset, ≤72 h; ROM, rupture of membrane; RR, relative risk.