Figure 3. Forced hypothermia leads to a decrease in the number of circulating lymphocytes.
The peripheral blood lymphocyte (A), T lymphocyte (B), and B lymphocyte (C) counts were measured in euthermic controls (EU), 5′-AMP-treated mice, or anesthetized mice, whose body temperature was lowered to ±24°C. Mice in forced hypothermia were injected with saline or with an A2BR antagonist (1.25 mg/kg and 12.5 mg/kg MRS1754), 30 min prior to cooling. Bars represent mean ± sem. Circles represent data from individual mice; */** = P < 0.05/0.01, respectively (n=7–9 animals/group where bars are shown). df, Degrees of freedom.