Figure 8. ε154RKR156 plays a role in PKC-ε phagosomal localization.

Macrophages were transfected with the indicated constructs (A) and subjected to synchronized phagocytosis. (B) ε161AAA163, but not ε154AAA156, concentrated at phagosomes; representative images showing red BIgG (upper) and the same image represented in gray scale (lower). Asterisks designate phagosomes. (C) LI was calculated as detailed in Materials and Methods. Data are presented as mean ± sem (60 total events from two experiments). Statistical significance was determined by ANOVA with Tukey's post-test. ***P < 0.001.