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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Feb 28;33(5):1092–1097. doi: 10.1161/ATVBAHA.112.301089

Table 1.

Baseline Characteristics of Men with Incident Lower Extremity Peripheral Artery Disease (Cases) and Matched Controls

Characteristic Cases (n=143) Controls (n=429) P
Age, y 65.4 (8.1) 65.3 (8.1) Matched
Smoking status, n (%)
 Current 32 (22) 90 (21)
 Past 78 (55) 242 (56) Matched
 Never 23 (16) 82 (19)
Total adiponectin, μg/mL 4.1 (3.2-5.5) 5.4 (3.8-7.5) <0.001
HDL cholesterol, mg/dL 41.7 (11.5) 48.5 (14.2) <0.001
LDL cholesterol, mg/dL 139.2 (34.8) 131.4 (33.3) 0.04
Triglycerides, mg/dL 143 (105-195) 115 (80-165) 0.001
Hemoglobin A1c*, % 5.56 (5.34-5.96) 5.41 (5.24-5.59) <0.001
C-reactive protein, mg/dL 2.24 (1.18-3.52) 1.18 (0.51-2.26) 0.02
Cystatin C, mg/dL 1.04 (0.91-1.22) 0.96 (0.86-1.07) <0.001
Creatinine, mg/dL 0.89 (0.80-1.02) 0.87 (0.78-0.96) 0.04
eGFR, mL·min−1·1.73 m−2 ** 86.8 (74.3-96.4) 89.9 (82.3-96.3) 0.02
Gamma-glutamyltransferase, U/L 27 (20-36) 23.0 (17-31) 0.15
Pack-years of smoking, y 26 (5-45) 18 (1-35) <0.001
History of diabetes, n (%) 28 (20) 16 (4) <0.001
History of hypertension, n (%) 70 (49) 130 (30) <0.001
History of hypercholesterolemia, n (%) 82 (57) 187 (44) 0.005
Parental history of myocardial infarction
before age 60 y, n (%)
22 (15) 44 (10) 0.09
Body mass index, kg/m2 25.8 (3.3) 25.6 (4.4) 0.48
Physical activity, MET-h/wk 22.7 (8.0-43.8) 27.4 (10.3-52.8) 0.003
Alcohol consumption, g/day 7.6 (0.9-17.8) 9.8 (1.8-20.3) 0.55

Data are expressed as mean (standard deviation), median (interquartile range) or number (percentage). P values are derived from generalized linear mixed models for continuous variables and Cochran-Mantel-Haenszel tests for categorical variables controlling for matched sets. Age, smoking status, fasting status and month of blood sampling were matching variables. Abbreviations: HDL, high-density lipoprotein; LDL, low-density lipoprotein; eGFR, estimated glomerular filtration rate; MET-h, metabolic equivalent task-hours.

*

Data was missing for one case and four controls.

**

eGFR was calculated according to the Chronic Kidney Disease Epidemiology Collaboration equation.