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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: J Immunother. 2013 May;36(4):248–257. doi: 10.1097/CJI.0b013e3182943549

FIGURE 2.

FIGURE 2

Flow cytometry analysis of cells in peritoneal lavages (PL) and peritoneal lymph nodes (LN) from treated and control mice with ID8 tumors (2-3 mice/group) and of cells from tumor-draining lymph nodes (TLN) and tumor infiltrating lymphocytes (TIL) from mice with SW1 tumors (2-3 mice/group). Administration of the 3 mAb combination decreased the frequency of CD19+ cells (Panel a) and increased CD3+ (Panel b), CD4+ (Panel c) and CD8+ (Panel d) cells in both tumor models. Intracellular cytokine staining shows that TNFα and IFNγ expression increased significantly in CD4+ (Panel e) and CD8+ (Panel f) cells. Representative dot plots from 3 similar experiments are shown in Supplemental Figure S2. n=5, * p<0.05, ** p<0.01, *** p <0.001.