Table 2. FcRγ-associated receptors.
Name | Species | Cell expression | Expression in osteoclast | Ligand |
---|---|---|---|---|
DCAR | Human, mouse | DCs | ? | |
PIR-A multiple isoforms (>six genes) | Mouse | B cells, DCs, monocytes/macrophages, granulocytes, mast cells, megakaryocytes/platelets | + | H2-D, H2K |
ILT/LIR | Human | NK cells, T-cell subsets, B cells, macrophages, mast cells, DCs | ? | |
mOSCAR ILT1/LIR7/LILRA2 LIR6/LILRA1 ILT8/LILRB6 ILT10/LILRA5 ILT11/LILRB7 ILT7/LILRA4 | Mouse | Osteoclasts | + | Collagen |
hOSCAR | Human | DCs and osteoclasts | + | Collagen |
FcαR | Eosinopohils, DCs, basophils, monocytes, macrophages, neutrophils | ? | IgA | |
FcγRIII | Macrophages and NK cells | + | IgG | |
FcεRI | Mast cells | ? | IgE | |
KIR2DLY | NK cells and some T cells | ? | ||
NKp46 |
|
NK cells |
? |
|
Abbreviations: DCs, dendritic cells; Ig, immunoglobin; IL, interleukin; NK cells, natural killer cells; PIR-A, immunoglobulin-like receptor-A; H2-D/H2K, histocompatability 2, D or K region.