Table 2.

Notch expression in different types of gastric cancer

Notch receptors and Notch ligands	Type of gastric cancer	The role of Notch proteins in gastric cancer pathogenesis
Notch1	premalignant and cancer tissue: intestinal metaplasia and well differentiated intestinal type of gastric cancer	crucial role in promoting metaplastic transition of gastric epithelial cells and in maintaining constant proliferation of intestinalized epithelial cells
Notch2	intestinal and diffuse type	–
DLL1	diffuse and mixed type	–
Notch3 Jagged	intestinal type	–