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. 2013 Feb 11;22(13):1921–1931. doi: 10.1089/scd.2012.0575

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Copyright 2013, Mary Ann Liebert, Inc.

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FIG. 1. — Macroscopic overview of injured and regenerating newt hearts. (A) The newt heart consists of an atrium (a), a ventricle (v), and an aortic trunk (t). The surface is partially covered by melanocytes. (B) Immediately after mechanical injury of the right half of the ventricle (0 dpi), the injured region appears red, probably due to restricted blood transport. (C–E) Restricted blood flow is visible up to 21 dpi when the size of the injured area decreases. (F) Further improvement of the injured area five weeks after damage. (G–I) At 84 dpi and afterward, no macroscopic differences between the damaged and undamaged hearts are visible. Dashed lines separate the injured from the uninjured region.