Figure 4.
(A) Effect of aflibercept and bevacizumab on luciferase activity in cells expressing VEGFR-1 stimulated by VEGF-A 121.38 (B) Effect of aflibercept and bevacizumab on luciferase activity in cells expressing VEGFR-1 stimulated by VEGF-A 165.38 (C) Effect of aflibercept and bevacizumab on luciferase activity in cells expressing VEGFR-1 stimulated by PlGF.38
Adapted from Papadopoulos N. Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab. Angiogenesis. 2012;15(2):171–185. The article/figure is published under Creative Commons License 2.0 CC-BY.38
Abbreviations: RLU, relative luciferase units; VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor.