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. Author manuscript; available in PMC: 2013 Jun 18.
Published in final edited form as: Nat Protoc. 2012 Apr 12;7(5):872–881. doi: 10.1038/nprot.2012.024

Figure 3.

Figure 3

In vivo metabolomics profiling. (a) The PCA clustering from extracted polar metabolites from cerebrospinal fluid (CSF) from 20 patients, 10 of which present with gliomas. Different disease stages are highlighted. (b) Hierarchical clustergram from polar metabolites that were extracted from formalin-fixed paraffin-embedded (FFPE) tissue cores from normal (Norm) lung and kidney tissue and from acute myeloid leukemia (AML) from kidney and lymphangioleiomyomatosis (LAM) lung disease. The data show that distinct clusters can be obtained from fixed tissue samples.