Table 1.
Body weight and blood metabolites of female SD and KD mice
| |
|
Weight |
Glucose |
Ketone |
Cholesterol |
Triglyceride |
Num. of |
|---|---|---|---|---|---|---|---|
| [gr] | [mmol/L] | [mmol/L] | [mmol/L] | [mmol/L] | embryos | ||
| Prior to |
SD |
29.5±0.5 (20) |
6.4±0.3 (20) |
0.25±0.02 (20) |
3.4±0.2 (20) |
2.1±0.2 (20) |
- |
| Mating |
KD |
30.8±0.7 (20) |
5.3±0.2 (20) * |
1.94±0.15 (20) * |
4.4±0.2 (17) * |
1.8±0.1 (17) * |
- |
| At E13.5 |
SD |
45.0±1.3 (11) |
7.0±0.5 (11) |
0.22±0.04 (11) |
2.8±0.1 (10) |
2.8±0.2 (10) |
12.9±0.6 (17) |
| |
KD |
45.4±1.2 (11) |
6.6±0.5 (11) |
1.57±0.23 (11) * |
3.6±0.2 (11) * |
5.1±1.1 (11) * |
12.1±1.0 (12) |
| At E17.5 |
SD |
67.1±1.7 (19) |
5.9±0.3 (12) |
0.27±0.04 (11) |
2.0±0.1 (13) |
2.7±0.3 (13) |
10.9±1.2 (8) |
| |
KD |
58.9±1.1 (18) * |
2.8±0.2 (11) * |
3.96±0.30 (11) * |
2.8±0.3 (12) * |
7.8±1.8 (12) * |
11.3±0.6 (6) |
| p-value |
Diet |
0.0094 |
< 0.0001 |
< 0.0001 |
< 0.0001 |
0.0569 |
– |
| |
Time-pt |
< 0.0001 |
0.0055 |
0.0001 |
< 0.0001 |
0.0011 |
– |
| Interaction | 0.0008 | 0.0411 | 0.0001 | 0.0273 | 0.0481 | – |
Values were measured just prior to mating, at E13.5 and at E17.5 (Mean ± SEM (Number of dams tested)). Statistically significant KD vs. SD p-values are indicated by a (*) for comparison at each time point.