Table 3.
ALE clusters associated with sympathetic and parasympathetic regulation
| Anatomical region | L/R | Size (mm3) | Max. ALE score | MNI coordinates (in mm) |
||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Sympathetic | ||||||
| Midcingulate cortex, paracingulate cortex, supplementary motor area | L/R | 15,408 | 0.0190 | 0 | 10 | 40 |
| Supramarginal gyrus, superior parietal lobule, primary somatosensory cortex | R | 8624 | 0.0128 | 48 | −26 | 46 |
| Amygdala, subgenual anterior cingulate cortex, nucleus accumbens, caudate, hippocampal formation | L | 4784 | 0.0114 | −20 | −8 | −12 |
| Ventromedial prefrontal cortex, pregenual/subgenual anterior cingulate cortex | L/R | 4384 | 0.0129 | −2 | 38 | −18 |
| Anterior insula, ventrolateral prefrontal cortex | R | 3912 | 0.0125 | 44 | 18 | −6 |
| Thalamus (medial–dorsal nucleus), nucleus ruber, periaqueductal gray | L/R | 3856 | 0.0094 | −4 | −16 | 6 |
| Supramarginal gyrus, superior parietal lobule, primary somatosensory cortex | L | 3432 | 0.0085 | −44 | −36 | 42 |
| Secondary somatosensory cortex, posterior insula, putamen | L | 3176 | 0.0099 | −32 | −20 | 14 |
| Cerebellum (lobulus crus I) | L | 3112 | 0.0122 | −46 | −66 | −28 |
| Dorsolateral prefrontal cortex | R | 2984 | 0.0088 | 20 | 36 | 34 |
| Parasympathetic | ||||||
| Hippocampal formation | R | 8416 | 0.0096 | 30 | −22 | −16 |
| Amygdala, ventral tegmental area, hypothalamus | L | 5784 | 0.0124 | −20 | −6 | −18 |
| Anterior insula, caudate | L | 5376 | 0.0072 | −40 | 0 | 12 |
| Precuneus, dorsal posterior cingulate cortex | L/R | 5360 | 0.0084 | −6 | −44 | 34 |
| Primary motor cortex, temporal pole | L | 5176 | 0.0115 | −56 | 6 | 8 |
| Medial temporal gyrus, superior temporal gyrus | R | 4024 | 0.0071 | 50 | −24 | 2 |
| Supramarginal gyrus, angular gyrus | R | 4008 | 0.0078 | 44 | −38 | 14 |
| Cerebellum (lobuli VI and vermis VI) | L | 3960 | 0.0070 | −10 | −62 | −20 |
| Anterior insula | R | 3752 | 0.0072 | 40 | 2 | 12 |
There were 19 studies, 296 subjects, and 172 foci, 9.57 mm FWHM, for EDA; 8 studies, 106 subjects, and 94 foci, 10.00 mm FWHM, for HF-HRV; and 1000 permutations. p < 0.05 is the cluster-forming threshold and the cluster threshold. L, Left; R, right.