Table 4.
ALE clusters of the conjunction analyses for the three task types and the two ANS divisions showing sympathetic and parasympathetic contributions to CAN modulatory regions observed for different tasks
| Anatomical region | L/R | Size (mm3) | Max. ALE score | MNI coordinates (in mm) |
||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Cognitive and sympathetic | ||||||
| Midcingulate cortex, paracingulate cortex, supplementary motor area | L/R | 7960 | 0.0120 | −2 | 16 | 44 |
| Anterior insula, frontal operculum, temporal pole | R | 1752 | 0.0078 | 48 | 18 | −6 |
| Cerebellum (lobulus crus I) | L | 1648 | 0.0106 | −46 | −64 | −26 |
| Secondary somatosensory cortex, posterior insula | L | 1576 | 0.0092 | −38 | −12 | 12 |
| Ventromedial prefrontal cortex, subgenual anterior cingulate cortex | L/R | 1352 | 0.0088 | −4 | 38 | −16 |
| Superior parietal lobule, supramarginal gyrus | L | 1304 | 0.0077 | −32 | −48 | 42 |
| Amygdala | L | 656 | 0.0051 | −22 | −8 | −16 |
| Cognitive and parasympathetic | ||||||
| Amygdala | L | 480 | 0.0051 | −22 | −8 | −16 |
| Anterior insula | R | 400 | 0.0054 | 34 | 20 | 4 |
| Affective and sympathetic | ||||||
| Amygdala | L | 3184 | 0.0114 | −20 | −8 | −12 |
| Supramarginal gyrus, primary somatosensory cortex | R | 2752 | 0.0089 | 48 | −26 | 44 |
| Posterior midcingulate cortex | L/R | 2616 | 0.0084 | 4 | 0 | 48 |
| Anterior insula, ventrolateral prefrontal cortex | R | 2496 | 0.0103 | 38 | 24 | −20 |
| Secondary somatosensory cortex, posterior insula, putamen | L | 1872 | 0.0084 | −18 | −16 | 18 |
| Thalamus (mediodorsal nucleus) | L | 968 | 0.0072 | −6 | −12 | 4 |
| Supramarginal gyrus, angular gyrus, superior parietal lobule | R | 624 | 0.0067 | 38 | −46 | 36 |
| Affective and parasympathetic | ||||||
| Amygdala | L | 3920 | 0.0124 | −20 | −6 | −18 |
| Hippocampal formation, amygdala | R | 2840 | 0.0095 | 30 | −22 | −16 |
| Anterior insula, caudate | L | 2192 | 0.0071 | −30 | 26 | 8 |
| Anterior insula | R | 2184 | 0.0071 | 44 | 12 | 6 |
| Somatosensory–motor and sympathetic | ||||||
| Midcingulate cortex | L/R | 5392 | 0.0165 | 2 | 12 | 40 |
| Amygdala, hippocampus | L | 944 | 0.0082 | −18 | −8 | −16 |
| Supramarginal gyrus, angular gyrus | R | 784 | 0.0080 | 58 | −40 | 22 |
| Supplementary motor area | L | 704 | 0.0086 | −10 | 4 | 62 |
| Secondary somatosensory cortex, posterior insula | L | 664 | 0.0086 | −34 | −20 | 14 |
| Red nucleus, periaqueductal gray | L/R | 624 | 0.0057 | −2 | −16 | −8 |
| Ventromedial prefrontal cortex, pregenual/subgenual anterior cingulate cortex | L | 464 | 0.0061 | −4 | 38 | −12 |
| Ventromedial prefrontal cortex, pregenual/subgenual anterior cingulate cortex | R | 352 | 0.0059 | 8 | 42 | −6 |
| Somatosensory–motor and parasympathetic | ||||||
| Precuneus, dorsal posterior cingulate cortex | L/R | 2856 | 0.0076 | −6 | −42 | 32 |
| Amygdala, ventral tegmental area, hypothalamus | L | 2176 | 0.0083 | −18 | −8 | −16 |
| Anterior insula | R | 1984 | 0.0072 | 40 | 2 | 12 |
| Anterior insula | L | 1304 | 0.0072 | −40 | 0 | 12 |
| Angular gyrus | R | 1104 | 0.0063 | 58 | −50 | 22 |
| Hippocampal formation | R | 1024 | 0.0055 | 22 | −12 | −20 |
| Cerebellum (lobulus vermis VI) | R | 144 | 0.0055 | −2 | −72 | −24 |
There were 11 studies, 145 subjects, and 165 foci for cognitive stimuli/tasks; 12 studies, 230 subjects, and 107 foci for affective stimuli/tasks; 13 studies, 136 subjects, and 245 foci for somatosensory–motor stimuli/tasks; 19 studies, 296 subjects, and 172 foci for EDA; and 8 studies, 106 subjects, and 94 foci for HFHRF. L, Left; R, right.