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. 2013 Jul;5(7):a012567. doi: 10.1101/cshperspect.a012567

Figure 3.

Figure 3.

Nucleotide substitution frequencies at the 5′ end of Neanderthal sequences. The frequencies of all possible differences to the human reference genome sequence are plotted in relation to their location in Neanderthal DNA sequences. Cytosine to thymine substitutions are the most frequent, and they occur most often at ends of molecule. All remaining nucleotide substitutions are indicated by the black line.