Table 4.

Functional annotation clusters of genes differentially expressed in response to thermal stress by alternative (2La or 2L+^a) karyotypes

Stress responsive genes	Annotation Cluster (representative annotation terms)	Gene count	Enrichment score
2La/Up	1 Proteasome complex	45	4.47
	2 Translation/translation initiation factor	33	3.79
	3 Tetratricopeptide (TPR) repeat	14	3.56
	4 Protein catabolism	53	3.31
	5 Tricarboxylic acid (TCA) cycle/cellular respiration	25	3.11
	6 PCI (proteasome, CSN, eIF3) domain	9	2.94
	7 Proteosome complex/proteolysis	50	2.92
	8 Chaperonin (Cpn60/TCP-1)	10	2.77
	9 ATP binding	75	1.97
	10 U-box/ubiquitin ligase	19	1.92
	11 Beta-ketoacyl synthase (fatty acid biosynthesis)	4	1.68
2La/Down	---	---	---
2L+a/Up	---	---	---
2L+a/Down	12 TCP-1/cpn60 chaperonin	6	2.32
	13 Proteasome/proteolysis	36	2.28
	14 Protein transport/localization	9	1.31