Figure 3.

70-gene risk score can increase in relapsed relative to newly diagnosed disease and an increase predicts poor post-relapse survival. (a) The 70-gene risk score in paired diagnostic (blue) and relapse (red) samples of 51 patients. The gene expression risk score is indicated to the left. Sample pairs are order from left to right based on lowest baseline score. (b) Kaplan–Meier plot of post-relapse survival of the three groups defined by low risk both at diagnosis and relapse (low-low), low risk at diagnosis and high risk at relapse (low-high), and high risk at both time points (high-high). Reproduced with Permission from Blood.